Angiotensin I Converting Enzyme 1 anticorps (AA 30-270)

N° du produit ABIN3016740

L’anticorps anti-Angiotensin I Converting Enzyme 1 Polyclonal Lapin est utilisé pour la détection de Angiotensin I Converting Enzyme 1 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Angiotensin I Converting Enzyme 1 anticorps (AA 30-270) (ABIN3016740)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Épitope: AA 30-270

Séquence: EASQQVTVTH GTSSQATTSS QTTTHQATAH QTSAQSPNLV TDEAEASKFV EEYDRTSQVV WNEYAEANWN YNTNITTETS KILLQKNMQI ANHTLKYGTQ ARKFDVNQLQ NTTIKRIIKK VQDLERAALP AQELEEYNKI LLDMETTYSV ATVCHPNGSC LQLEPDLTNV MATSRKYEDL LWAWEGWRDK AGRAILQFYP KYVELINQAA RLNGYVDAGD SWRSMYETPS LEQDLERLFQ E

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 30-270 of human ACE11 (NP_690043.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE

Sujet: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.,ACE,ACE1,CD143,DCP,DCP1,angiotensin-converting enzyme,ICH,MVCD3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Blood,Serum Proteins,Hypoxia,ACE

Poids moléculaire: 78 kDa/83 kDa/131 kDa/149 kDa

ID gène: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration