ELK1 anticorps (pSer383)
Aperçu rapide pour ELK1 anticorps (pSer383) (ABIN155121)
Antigène
Voir toutes ELK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer383
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Specificité
- The antibody detects 62 kDa phosphorylated Elk-1 (Ser383).
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Purification
- Affinity purified
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Immunogène
- Synthetic peptide surrounding amino acid 383 of human Elk-1.
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Indications d'application
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
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Autre désignation
- ELK1
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Sujet
- Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 (Ser383) is also a target of the stress-activated kinase SAPK/JNK.Synonyms: ETS domain-containing protein Elk-1, Elk-1
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ID gène
- 2002
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NCBI Accession
- NP_001107595
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UniProt
- P19419
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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