VEGFR2/CD309 anticorps (Soluble)

N° du produit ABIN1589863

Cet anticorps Lapin Polyclonal détecte spécifiquement VEGFR2/CD309 dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour VEGFR2/CD309 anticorps (Soluble) (ABIN1589863)

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFR2/CD309 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VEGFR2/CD309 anticorps

Épitope: Soluble

Fonction: Rabbit Anti-Mouse VEGFR-2/Flk-1 (Peptide), soluble Polyclonal Antibody

Specificité: Peptide: GMEASLGDRIAMP

Attributs du produit: Chromosomal location: 5 C3.3, 5 42.0 cM
Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP).

Purification: Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.

Immunogène: peptide: GMEASLGDRIAMP

Isotype: IgG

Information d'application

Indications d'application: Western Blot: use at 1-5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur VEGFR2/CD309

Antigène: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Autre désignation: VEGFR-2/Flk-1

Sujet:

Synonyms: soluble vascular endothelial growth factor receptor-2 , soluble Kdr, soluble Ly73, soluble Flk-1, sVEGFR2, sVEGF receptor 2, soluble kinase insert domain protein receptor

Description: The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle, other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C, ligand binding plays a key role in vascular development and vascular permeability.

ID gène: 16542

UniProt: P35918

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling