CRYAA anticorps (AA 1-173)
Aperçu rapide pour CRYAA anticorps (AA 1-173) (ABIN361018)
Antigène
Voir toutes CRYAA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-173
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Fonction
- Human Crystallin alpha A/CRYAA antibody
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Purification
- Purified
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Immunogène
- Recombinant human Crystallin alpha A (1-173aa) purified from E. coli
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Isotype
- IgG1 kappa
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Indications d'application
- Recommended dilution 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing cycles
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CRYAA (Crystallin, alpha A (CRYAA))
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Autre désignation
- Crystallin alpha A/CRYAA
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Sujet
- Alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively. alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and the participation in the intracellular architecture.
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NCBI Accession
- NP_000385
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Pathways
- M Phase
Antigène
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