Angiopoietin 1 anticorps
Aperçu rapide pour Angiopoietin 1 anticorps (ABIN1678801)
Antigène
Voir toutes Angiopoietin 1 (ANGPT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human ANGPT1
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Angiopoietin 1 (ANGPT1)
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Autre désignation
- ANGPT1
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Sujet
- This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015],AGP1, AGPT, ANG1,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Growth factors,Hypoxia,ANGPT1
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Poids moléculaire
- 57 kDa
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ID gène
- 284
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UniProt
- Q15389
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Pathways
- Signalisation RTK, Glycosaminoglycan Metabolic Process
Antigène
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