CD8B anticorps (AA 22-170)

N° du produit ABIN1679102

Détail du produit anti-CD8B anticorps

Antigène: CD8B (CD8b Molecule (CD8B))

Épitope: AA 22-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8B est non-conjugé

Application: Western Blotting (WB)

Séquence: LQQTPAYIKV QTNKMVMLSC EAKISLSNMR IYWLRQRQAP SSDSHHEFLA LWDSAKGTIH GEEVEQEKIA VFRDASRFIL NLTSVKPEDS GIYFCMIVGS PELTFGKGTQ LSVVDFLPTT AQPTKKSTLK KRVCRLPRPE TQKGPLCSP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 22-170 of human CD8B (NP_757362.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD8B

Antigène: CD8B (CD8b Molecule (CD8B))

Autre désignation: CD8B (CD8B Produits)

Synonymes: anticorps Cd8b, anticorps Ly-3, anticorps Ly-C, anticorps Lyt-3, anticorps CD8B1, anticorps LEU2, anticorps LY3, anticorps LYT3, anticorps P37, anticorps Cd8b1, anticorps CD8b molecule, anticorps CD8 antigen, beta chain 1, anticorps Cd8b, anticorps CD8B, anticorps Cd8b1

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.,CD8B,CD8B1,LEU2,LY3,LYT3,P37,Immunology & Inflammation,CD markers,CD8B

Poids moléculaire: 20 kDa/22 kDa/23 kDa/24 kDa/25 kDa/27 kDa

ID gène: 926

UniProt: P10966

Pathways: TCR Signaling