Claudin 11 anticorps (AA 26-207)

N° du produit ABIN1679255

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 11 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Claudin 11 anticorps (AA 26-207) (ABIN1679255)

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Claudin 11 anticorps

Épitope: AA 26-207

Séquence: STNDWVVTCG YTIPTCRKLD ELGSKGLWAD CVMATGLYHC KPLVDILILP GYVQACRALM IAASVLGLPA ILLLLTVLPC IRMGQEPGVA KYRRAQLAGV LLILLALCAL VATIWFPVCA HRETTIVSFG YSLYAGWIGA VLCLVGGCVI LCCAGDAQAF GENRFYYTAG SSSPTHAKSA HV

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 26-207 of human CLDN11 (NP_005593.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: CLDN11

Sujet: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN11,OSP,OTM,Immunology & Inflammation,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Oligodendrocyte marker,CLDN11

Poids moléculaire: 21 kDa

ID gène: 5010

UniProt: O75508

Pathways: Hepatitis C