DOCK2 anticorps (AA 1551-1830)
Aperçu rapide pour DOCK2 anticorps (AA 1551-1830) (ABIN1679578)
Antigène
Voir toutes DOCK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1551-1830
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Séquence
- FTEEYVRDHP EDQDKLTHLK DLIAWQIPFL GAGIKIHEKR VSDNLRPFHD RMEECFKNLK MKVEKEYGVR EMPDFDDRRV GRPRSMLRSY RQMSIISLAS MNSDCSTPSK PTSESFDLEL ASPKTPRVEQ EEPISPGSTL PEVKLRRSKK RTKRSSVVFA DEKAAAESDL KRLSRKHEFM SDTNLSEHAA IPLKASVLSQ MSFASQSMPT IPALALSVAG IPGLDEANTS PRLSQTFLQL SDGDKKTLTR KKVNQFFKTM LASKSAEEGK QIPDSLSTDL
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1551-1830 of human DOCK2 (NP_004937.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:1000,IF,1:50 - 1:200,IP,1:50 - 1:100
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
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Autre désignation
- DOCK2
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Sujet
- The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.,DOCK2,IMD40,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Hematopoietic Progenitors,DOCK2
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Poids moléculaire
- 38 kDa/211 kDa
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ID gène
- 1794
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UniProt
- Q92608
Antigène
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