DOCK2 anticorps (Internal Region)

N° du produit ABIN7220070

L’anticorps anti-DOCK2 Polyclonal Lapin est utilisé pour la détection de DOCK2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, ELISA et IF.

Aperçu rapide pour DOCK2 anticorps (Internal Region) (ABIN7220070)

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DOCK2 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-DOCK2 Polyclonal Antibody

Specificité: DOCK2 Polyclonal Antibody detects endogenous levels of DOCK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human DOCK2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur DOCK2

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Autre désignation: DOCK2

Sujet: DOCK2, KIAA0209, Dedicator of cytokinesis protein 2Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.

ID gène: 1794

UniProt: Q92608