DOCK2 anticorps (C-Term)

N° du produit ABIN6261347

Détail du produit anti-DOCK2 anticorps

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: DOCK2 Antibody detects endogenous levels of total DOCK2.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DOCK2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DOCK2

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Autre désignation: DOCK2 (DOCK2 Produits)

Synonymes: anticorps AI662014, anticorps AW122239, anticorps CED-5, anticorps Hch, anticorps MBC, anticorps dedicator of cytokinesis 2, anticorps dedicator of cyto-kinesis 2, anticorps DOCK2, anticorps dock2, anticorps Dock2

Sujet:

Description: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Gene: DOCK2

Poids moléculaire: 212 kDa

ID gène: 1794

UniProt: Q92608