EPOR anticorps (AA 274-508)

N° du produit ABIN1679741

Détail du produit anti-EPOR anticorps

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Épitope: AA 274-508

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPOR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: HRRALKQKIW PGIPSPESEF EGLFTTHKGN FQLWLYQNDG CLWWSPCTPF TEDPPASLEV LSERCWGTMQ AVEPGTDDEG PLLEPVGSEH AQDTYLVLDK WLLPRNPPSE DLPGPGGSVD IVAMDEGSEA SSCSSALASK PSPEGASAAS FEYTILDPSS QLLRPWTLCP ELPPTPPHLK YLYLVVSDSG ISTDYSSGDS QGAQGGLSDG PYSNPYENSL IPAAEPLPPS YVACS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 274-508 of human EPOR (NP_000112.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-EPOR (ABIN1679741)

Kai-lan, Si: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." dans: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).

Détails sur EPOR

Antigène: EPOR (Erythropoietin Receptor (EPOR))

Autre désignation: EPOR (EPOR Produits)

Synonymes: anticorps EPOR, anticorps epor, anticorps EPO-R, anticorps erythropoietin receptor, anticorps erythropoietin receptor L homeolog, anticorps EPOR, anticorps epor, anticorps Epor, anticorps epor.L

Sujet: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.,EPOR,EPO-R,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Heart,Hypertrophy,EPOR

Poids moléculaire: 26 kDa/35 kDa/55 kDa

ID gène: 2057

UniProt: P19235

Pathways: Signalistation JAK/STAT