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EPOR anticorps (AA 301-450)

EPOR Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN686347
  • Antigène Voir toutes EPOR Anticorps
    EPOR (Erythropoietin Receptor (EPOR))
    Épitope
    • 15
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-450
    Reactivité
    • 119
    • 58
    • 48
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 106
    • 17
    • 5
    • 1
    Lapin
    Clonalité
    • 114
    • 15
    Polyclonal
    Conjugué
    • 63
    • 15
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPOR est non-conjugé
    Application
    • 89
    • 45
    • 24
    • 23
    • 22
    • 15
    • 13
    • 13
    • 11
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EPOR
    Isotype
    IgG
    Top Product
    Discover our top product EPOR Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Li, Chen, Shao, Tang, Chen, Chen, Xu: "Oxidative stress induces the decline of brain EPO expression in aging rats." dans: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).

    Zhong, Zhang: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." dans: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).

  • Antigène
    EPOR (Erythropoietin Receptor (EPOR))
    Autre désignation
    EPOR (EPOR Produits)
    Synonymes
    anticorps EPOR, anticorps epor, anticorps EPO-R, anticorps erythropoietin receptor, anticorps erythropoietin receptor L homeolog, anticorps EPOR, anticorps epor, anticorps Epor, anticorps epor.L
    Sujet

    Synonyms: EPO-R, Erythropoietin receptor, EPOR

    Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

    ID gène
    2057
    UniProt
    P19235
    Pathways
    Signalistation JAK/STAT
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