GFRA2 anticorps (AA 320-400)

N° du produit ABIN7228652

L’anticorps anti-GFRA2 Polyclonal Lapin est utilisé pour la détection de GFRA2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour GFRA2 anticorps (AA 320-400) (ABIN7228652)

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GFRA2 anticorps

Épitope: AA 320-400

Fonction: Rabbit Anti-GFRA2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of GFRA2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human GFRA2 protein at AA range: 320-400

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GFRA2

Antigène: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Autre désignation: GFRA2

Sujet: GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. GFRA2 is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for GFRA2.

Poids moléculaire: 51kD

ID gène: 2675

UniProt: O00451