POLI anticorps (AA 50-350)
Aperçu rapide pour POLI anticorps (AA 50-350) (ABIN1682214)
Antigène
Voir toutes POLI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-350
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Séquence
- ASSRVIVHVD LDCFYAQVEM ISNPELKDKP LGVQQKYLVV TCNYEARKLG VKKLMNVRDA KEKCPQLVLV NGEDLTRYRE MSYKVTELLE EFSPVVERLG FDENFVDLTE MVEKRLQQLQ SDELSAVTVS GHVYNNQSIN LLDVLHIRLL VGSQIAAEMR EAMYNQLGLT GCAGVASNKL LAKLVSGVFK PNQQTVLLPE SCQHLIHSLN HIKEIPGIGY KTAKCLEALG INSVRDLQTF SPKILEKELG ISVAQRIQKL SFGEDNSPVI LSGPPQSFSE EDSFKKCSSE VEAKNKIEEL L
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human POLI (NP_009126.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." dans: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." dans: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
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- POLI (Polymerase (DNA Directed) iota (POLI))
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Autre désignation
- POLI
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Sujet
- The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion.,POLI,RAD30B,RAD3OB,eta2,Epigenetics & Nuclear Signaling,POLI
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Poids moléculaire
- 83 kDa
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ID gène
- 11201
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UniProt
- Q9UNA4
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Pathways
- Réparation de l'ADN
Antigène
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