TIMELESS anticorps (AA 969-1208)
Aperçu rapide pour TIMELESS anticorps (AA 969-1208) (ABIN1683038)
Antigène
Voir toutes TIMELESS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 969-1208
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Séquence
- EDLEEEENLP EEDSEEEEEG GSEAEQVQGS LVLSNENLGQ SLHQEGFSIP LLWLQNCLIR AADDREEDGC SQAVPLVPLT EENEEAMENE QFQQLLRKLG VRPPASGQET FWRIPAKLSP TQLRRAAASL SQPEEEQKLQ PELQPKVPGE QGSDEEHCKE HRAQALRALL LAHKKKAGLA SPEEEDAVGK EPLKAAPKKR QLLDSDEEQE EDEGRNRAPE LGAPGIQKKK RYQIEDDEDD
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 969-1208 of human TIMELESS (NP_003911.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TIMELESS (Timeless Homolog (TIMELESS))
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Autre désignation
- TIMELESS
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Sujet
- The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.,TIMELESS,TIM,TIM1,hTIM,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,TIMELESS
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Poids moléculaire
- 138 kDa
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ID gène
- 8914
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UniProt
- Q9UNS1
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Pathways
- Protein targeting to Nucleus, Photoperiodism
Antigène
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