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FAK anticorps (pSer910) (Biotin)

PTK2 Reactivité: Souris, Rat, Xenopus laevis WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700480
  • Antigène Voir toutes FAK (PTK2) Anticorps
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Épitope
    • 39
    • 29
    • 27
    • 24
    • 23
    • 23
    • 20
    • 18
    • 16
    • 16
    • 12
    • 11
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer910
    Reactivité
    • 327
    • 284
    • 221
    • 23
    • 20
    • 17
    • 16
    • 13
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat, Xenopus laevis
    Hôte
    • 329
    • 26
    • 3
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 323
    • 39
    Polyclonal
    Conjugué
    • 176
    • 18
    • 16
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 13
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 1
    Cet anticorp FAK est conjugé à/à la Biotin
    Application
    • 298
    • 124
    • 122
    • 121
    • 107
    • 70
    • 69
    • 49
    • 30
    • 29
    • 22
    • 6
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat, Xenopus laevis
    Homologie
    Human,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr910
    Isotype
    IgG
    Top Product
    Discover our top product PTK2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Autre désignation
    FAK (PTK2 Produits)
    Synonymes
    anticorps FADK, anticorps FAK, anticorps FAK1, anticorps FRNK, anticorps PPP1R71, anticorps p125FAK, anticorps pp125FAK, anticorps PTK2, anticorps Fadk, anticorps mKIAA4203, anticorps fak, anticorps fak1a, anticorps ptk2, anticorps ptk2a, anticorps wu:fa18c04, anticorps zgc:66114, anticorps CG10023, anticorps CT28129, anticorps DFAK, anticorps DFak, anticorps DFak56, anticorps Dfak, anticorps Dfak56, anticorps DmFAK, anticorps Dmel\\CG10023, anticorps Fak56, anticorps Fak56D, anticorps fak56, anticorps protein tyrosine kinase 2, anticorps protein tyrosine kinase 2 L homeolog, anticorps PTK2 protein tyrosine kinase 2, anticorps protein tyrosine kinase 2ab, anticorps Focal adhesion kinase, anticorps PTK2, anticorps ptk2.L, anticorps Ptk2, anticorps ptk2ab, anticorps Fak
    Sujet

    Synonyms: FAK phospho S910, p-FAK phospho S910, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.

    Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

    ID gène
    5747
    Pathways
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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