Cyclin D3 anticorps (pThr283) (Cy3)

N° du produit ABIN1702561

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin D3 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin D3 anticorps (pThr283) (Cy3) (ABIN1702561)

Antigène: Cyclin D3 (CCND3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D3 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Cyclin D3 anticorps (Cy3)

Épitope: pThr283

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: Cyclin D3

Sujet:

Synonyms: Cyclin D3 phospho T283, Cyclin D3 phospho Thr283, p-Cyclin D3 T283, p-Cyclin D3 Thr283, p-Cyclin D3 phospho T283, CCND 3, Ccnd3, CCND3_HUMAN, CyclinD3, D3 type cyclin, G1 S specic cyclin D3, G1/S specic cyclin D3, G1/S-specic cyclin-D3.

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

ID gène: 896

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process