POLK anticorps (AA 1-100) (Cy3)

N° du produit ABIN1703041

Cet anticorps Lapin Polyclonal détecte spécifiquement POLK dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour POLK anticorps (AA 1-100) (Cy3) (ABIN1703041)

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLK est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-POLK anticorps (Cy3)

Épitope: AA 1-100

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur POLK

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Autre désignation: DNA Polymerase Kappa/POLK

Sujet:

Synonyms: DNA polymerase kappa, DINB protein, Short=DINP, POLK_HUMAN.

Background: DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.

ID gène: 51426

Pathways: Réparation de l'ADN