IFNAR1 anticorps (pTyr466) (FITC)

N° du produit ABIN1710772

Cet anticorps Lapin Polyclonal détecte spécifiquement IFNAR1 dans IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour IFNAR1 anticorps (pTyr466) (FITC) (ABIN1710772)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR1 est conjugé à/à la FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-IFNAR1 anticorps (FITC)

Épitope: pTyr466

Homologie: Human,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IFNAR1 around the phosphorylation site of Tyr466

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR1

Sujet:

Synonyms: Alpha type antiviral protein, AVP, Beta type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, N alpha REC, N alpha REC, N alpha receptor, N alpha/beta Receptor alpha, N beta receptor, Interferon alpha/beta receptor 1, N-alpha/beta receptor 1, N-R-1, NAR, NAR1, NBR, RC, INAR1_HUMAN, Interferon alpha beta and omega receptor 1, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor alpha chain, Interferon beta receptor 1, Type I interferon receptor 1.

Background: IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Pathways: Signalistation JAK/STAT, Hepatitis C