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HHAT anticorps (AA 101-200) (HRP)

HHAT Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711049
  • Antigène Voir toutes HHAT Anticorps
    HHAT (Hedgehog Acyltransferase (HHAT))
    Épitope
    • 14
    • 10
    • 7
    • 6
    • 1
    AA 101-200
    Reactivité
    • 32
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 32
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HHAT est conjugé à/à la HRP
    Application
    • 32
    • 13
    • 13
    • 13
    • 12
    • 12
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HHAT
    Isotype
    IgG
    Top Product
    Discover our top product HHAT Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HHAT (Hedgehog Acyltransferase (HHAT))
    Autre désignation
    HHAT (HHAT Produits)
    Synonymes
    anticorps RGD1311746, anticorps MART2, anticorps SKI1, anticorps Skn, anticorps 2810432O22Rik, anticorps AI462858, anticorps AP-2CRE, anticorps Tg(TFAP2A-cre)1Will, anticorps hedgehog acyltransferase, anticorps Hhat, anticorps HHAT, anticorps hhat
    Sujet

    Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.

    Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

    ID gène
    55733
    Pathways
    Signalisation Hedgehog
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