OAS3 anticorps (AA 901-1000) (HRP)

N° du produit ABIN1711390

Cet anticorps Lapin Polyclonal détecte spécifiquement OAS3 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour OAS3 anticorps (AA 901-1000) (HRP) (ABIN1711390)

Antigène: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAS3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-OAS3 anticorps (HRP)

Épitope: AA 901-1000

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OAS3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur OAS3

Antigène: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Autre désignation: OAS3

Sujet:

Synonyms: 2-5''oligoA synthase 3, 2 5' oligoA synthetase 3, 2 5'LIGO, 2 5A synthetase 3, 2''-5''-oligoadenylate synthase 3, 2-5A synthase 3, MGC133260, OAS3 2' 5' oligoadenylate synthetase 3, 100 kDa, OAS3, OAS3_HUMAN, p100, p100 OAS, p100OAS.

Background: The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2

ID gène: 4940

Pathways: Hepatitis C