Acetyl-CoA Carboxylase alpha anticorps (pSer80) (HRP)

N° du produit ABIN1711450

Cet anticorps Lapin Polyclonal détecte spécifiquement Acetyl-CoA Carboxylase alpha dans WB, ELISA et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour Acetyl-CoA Carboxylase alpha anticorps (pSer80) (HRP) (ABIN1711450)

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps (HRP)

Épitope: pSer80

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser80

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: Acetyl Coenzyme A Carboxylase alpha

Sujet:

Synonyms: Acetyl Coenzyme A Carboxylase alpha phospho S80, p-Acetyl Coenzyme A Carboxylase alpha phospho S80, ACAC, ACACA, ACACA, ACACA_HUMAN, ACC alpha, ACC, ACC-alpha, ACC1, ACC1, ACCA, acetyl CoA carboxylase 1, acetyl Coenzyme A, Acetyl Coenzyme A, Biotin carboxylase, Acetyl-Coenzyme A Carboxylase alpha.

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg