CTNND1 anticorps (pTyr228) (HRP)

N° du produit ABIN1711470

Cet anticorps anti-CTNND1 est un anticorps Lapin Polyclonal détectant CTNND1 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Souris.

Aperçu rapide pour CTNND1 anticorps (pTyr228) (HRP) (ABIN1711470)

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNND1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CTNND1 anticorps (HRP)

Épitope: pTyr228

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr228

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CTNND1

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Sujet:

Synonyms: delta 1 Catenin phospho Y228, p-delta 1 Catenin phospho Y228, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin cadherin associated protein delta 1, Catenin delta 1, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120Cas, p120Ctn, P120CAS, P120CTN.

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

ID gène: 1500

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling