FZD10 anticorps (PE)

N° du produit ABIN1712712

Cet anticorps anti-FZD10 est un anticorps Lapin Polyclonal détectant FZD10 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour FZD10 anticorps (PE) (ABIN1712712)

Antigène: FZD10 (Frizzled Family Receptor 10 (FZD10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD10 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-FZD10 anticorps (PE)

Specificité: Due to the similarity of this protein to Frizzled 9, there is a chance that this antibody will react with this protein based on homology.

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Frizzled 10/CD350

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Gentamicin sulfate

Précaution d'utilisation: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FZD10

Antigène: FZD10 (Frizzled Family Receptor 10 (FZD10))

Autre désignation: Frizzled 10/Cd350

Sujet:

Synonyms: Fz10, FzE7, CD350, FZ-10, hFz10, Frizzled-10, FZD10

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

ID gène: 11211

UniProt: Q9ULW2

Pathways: Signalisation WNT