Claudin 7 anticorps (PE)

N° du produit ABIN1712744

L’anticorps Lapin Polyclonal anti-Claudin 7 a été validé pour IF (p). Il convient pour détecter Claudin 7 dans des échantillons de Humain, Rat, Souris, Chien et Boeuf (Vache).

Aperçu rapide pour Claudin 7 anticorps (PE) (ABIN1712744)

Antigène: Claudin 7 (CLDN7)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 7 est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Claudin 7 anticorps (PE)

Réactivité croisée: Souris, Rat (Rattus), Chien, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human Claudin 7

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur Claudin 7

Antigène: Claudin 7 (CLDN7)

Autre désignation: Claudin 7

Sujet: The Claudin superfamily consists of many structurally related proteins in humans (1). These proteins are important structural and functional components of tight junctions in paracellular transport (1,2). Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1). Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and Junction adhesion molecule (3). Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4). Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (5). mRNA studies indicate that Claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis (6). The gene encoding human Claudin-7 maps to chromosome 17p13 (7).

ID gène: 1366

Pathways: Hepatitis C