ITGA2 anticorps (AA 801-900)

N° du produit ABIN1713632

L’anticorps Lapin Polyclonal anti-ITGA2 a été validé pour WB, ELISA et ICC. Il convient pour détecter ITGA2 dans des échantillons de Humain.

Aperçu rapide pour ITGA2 anticorps (AA 801-900) (ABIN1713632)

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-ITGA2 anticorps

Épitope: AA 801-900

Réactivité croisée: Humain

Homologie: Mouse,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin alpha 2/CD49b

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ITGA2

Antigène: ITGA2 (Integrin alpha 2 (ITGA2))

Autre désignation: Integrin alpha 2/CD49b

Sujet:

Synonyms: ITGA2, Integrin alpha 2, CD49b antigen, BR, CD 49b, CD49 antigen like family member B, CD49b, CD49b, Collagen receptor, DX5 , Glycoprotein Ia deficiency included, GP Ia, GP Ia deficiency, included, GPIa, HPA 5 included, HPA5 included, Platelet alloantigen Bra, included, Platelet antigen Br, Platelet glycoprotein GPIa, Platelet glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet membrane glycoprotein Ia, Platelet receptor for collagen, deficiency of, included, Very late activation protein 2 receptor alpha 2 subunit, VLA 2 alpha chain, VLA 2, VLA 2 subunit alpha, VLA2 alpha chain, ITA2_HUMAN.

Background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

ID gène: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex