ARHGEF11 anticorps (AA 451-550)

N° du produit ABIN1714955

L’anticorps anti-ARHGEF11 Polyclonal Lapin est utilisé pour la détection de ARHGEF11 dans des échantillons de Humain. Il a été validé pour WB, IHC (p), IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour ARHGEF11 anticorps (AA 451-550) (ABIN1714955)

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ARHGEF11 anticorps

Épitope: AA 451-550

Fonction: ARHGEF11 Polyclonal Antibody

Réactivité croisée: Humain

Homologie: Mouse,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ARHGEF11

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Autre désignation: PDZ RHOGEF/GTRAP48

Sujet:

Synonyms: PDZ-RhoGEF, ARHGB_HUMAN, ARHGEF 11, ARHGEF11, DKFZp667F1223, Glutamate transporter EAAT4 associated protein 48, GTRAP 48, GTRAP48, PDZ RhoGEF, Rho guanine exchange factor GEF 11, Rho guanine nucleotide exchange factor GEF 11, Rho guanine nucleotide exchange factor 11, RhoA specic guanine nucleotide exchange factor, RhoGEF glutamate transport modulator.

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling