BCL3 anticorps

N° du produit ABIN1721461

Cet anticorps Hamster Monoclonal détecte spécifiquement BCL3 dans WB, ELISA et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BCL3 anticorps (ABIN1721461)

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivité: Humain, Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 150-3-5

Détail du produit anti-BCL3 anticorps

Specificité: Reacts with human and mouse Bcl-3.

Purification: Purified

Immunogène: Recombinant mouse Bcl-3-6His.

Isotype: IgG1 lambda

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB2 μg/mL.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Dilute in PBS or medium that is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: Bcl-3

Sujet: The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IκB subfamily of inhibitors of NFκB transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NFκB1 and NFκB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFκB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.

B-cell lymphoma 3 protein homolog, BCL-3 Gene name: Bcl3

UniProt: Q9Z2F6

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus