Ret Proto-Oncogene anticorps (AA 896-1063)

N° du produit ABIN1724678

Il existe 2+ publications pour ce produit. L’anticorps anti-Ret Proto-Oncogene Monoclonal Souris est utilisé pour la détection de Ret Proto-Oncogene dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Ret Proto-Oncogene anticorps (AA 896-1063) (ABIN1724678)

Antigène: Ret Proto-Oncogene (RET)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ret Proto-Oncogene est non-conjugé

Application: ELISA

Clone: 8D10C9

Détail du produit anti-Ret Proto-Oncogene anticorps

Épitope: AA 896-1063

Fonction: RET Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Ret Proto-Oncogene (ABIN1724678)

Young, Anderson, Anderson: "Guidance cues involved in the development of the peripheral autonomic nervous system." dans: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).

Myers, Mulligan: "The RET receptor is linked to stress response pathways." dans: Cancer research, Vol. 64, Issue 13, pp. 4453-63, (2004) (PubMed).

Détails sur Ret Proto-Oncogene

Antigène: Ret Proto-Oncogene (RET)

Autre désignation: RET

Sujet: RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung

ID gène: 5979

UniProt: P07949

Pathways: Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation