PDE1B anticorps (AA 370-536)

N° du produit ABIN1724782

Cet anticorps Souris Monoclonal détecte spécifiquement PDE1B dans ELISA, IHC et FACS. Il présente une réactivité envers Humain et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour PDE1B anticorps (AA 370-536) (ABIN1724782)

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDE1B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 5C4A3

Détail du produit anti-PDE1B anticorps

Épitope: AA 370-536

Fonction: PDE1B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PDE1B (ABIN1724782)

Vandeput, Wolda, Krall, Hambleton, Uher, McCaw, Radwanski, Florio, Movsesian: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." dans: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).

Détails sur PDE1B

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Autre désignation: PDE1B

Sujet: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 61.4 kDa

ID gène: 5153

UniProt: Q01064

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma