MRPL42 anticorps (AA 142-203)

N° du produit ABIN1724803

Cet anticorps Souris Monoclonal détecte spécifiquement MRPL42 dans ELISA, IHC, WB, FACS et ICC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MRPL42 anticorps (AA 142-203) (ABIN1724803)

Antigène: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MRPL42 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3H6G11

Détail du produit anti-MRPL42 anticorps

Épitope: AA 142-203

Fonction: MRPL42 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MRPL42 (AA: 142-203) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MRPL42 (ABIN1724803)

Zhang, Gerstein: "Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome." dans: Genomics, Vol. 81, Issue 5, pp. 468-80, (2003) (PubMed).

Koc, Burkhart, Blackburn, Moyer, Schlatzer, Moseley, Spremulli: "The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present." dans: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 43958-69, (2001) (PubMed).

Détails sur MRPL42

Antigène: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Autre désignation: MRPL42

Sujet: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Poids moléculaire: 16.7 kDa

ID gène: 28977

UniProt: Q9Y6G3