Axin anticorps (C-Term)

N° du produit ABIN1732155

Détail du produit anti-Axin anticorps

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with human AXIN1

Purification: Antigen affinity purified

Immunogène: 14 amino acid peptide near the carboxy terminus of human AXIN1

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: IHC - P (5 μg/mL), WB (1 - 2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: AXIN1 (AXIN1 Produits)

Synonymes: anticorps AXIN1, anticorps axin, anticorps fused, anticorps xAxin, anticorps LOC100226467, anticorps AXIN, anticorps PPP1R49, anticorps AI316800, anticorps Axin, anticorps Fu, anticorps Kb, anticorps Ki, anticorps kinky, anticorps knobbly, anticorps AXIN1-RGS, anticorps wu:fi22e03, anticorps wu:fj14c08, anticorps wu:fk11b03, anticorps zgc:109872, anticorps axin 1, anticorps axin 1 S homeolog, anticorps axin 1 L homeolog, anticorps AXIN1, anticorps axin1.S, anticorps axin1.L, anticorps Axin1, anticorps axin1

Sujet: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling