Axin anticorps (C-Term)

N° du produit ABIN1732156

Cet anticorps Chèvre Polyclonal détecte spécifiquement Axin dans ELISA et IHC (p). Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache) et Chien.

Aperçu rapide pour Axin anticorps (C-Term) (ABIN1732156)

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Axin anticorps

Épitope: C-Term

Specificité: Reacts with the C-terminus part of human AXIN1

Réactivité croisée: Souris, Boeuf (Vache), Chien, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.

Purification: Antigen affinity purified

Immunogène: Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)

Information d'application

Indications d'application:

Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Minimize freezing and thawing.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: AXIN1

Sujet: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling