Axin anticorps (C-Term)

N° du produit ABIN1732156

Détail du produit anti-Axin anticorps

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Axin est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Reacts with the C-terminus part of human AXIN1

Réactivité croisée: Souris, Boeuf (Vache), Chien, Rat (Rattus)

Réactivité croisée (Details): Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.

Purification: Antigen affinity purified

Immunogène: Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)

Information d'application

Indications d'application:

Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Minimize freezing and thawing.

Détails sur Axin

Antigène: Axin (AXIN1) (Axin 1 (AXIN1))

Autre désignation: AXIN1 (AXIN1 Produits)

Synonymes: anticorps AXIN1, anticorps axin, anticorps fused, anticorps xAxin, anticorps LOC100226467, anticorps AXIN, anticorps PPP1R49, anticorps AI316800, anticorps Axin, anticorps Fu, anticorps Kb, anticorps Ki, anticorps kinky, anticorps knobbly, anticorps AXIN1-RGS, anticorps wu:fi22e03, anticorps wu:fj14c08, anticorps wu:fk11b03, anticorps zgc:109872, anticorps axin 1, anticorps axin 1 S homeolog, anticorps axin 1 L homeolog, anticorps AXIN1, anticorps axin1.S, anticorps axin1.L, anticorps Axin1, anticorps axin1

Sujet: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.

UniProt: O15169

Pathways: Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling