EPH Receptor A2 anticorps

N° du produit ABIN179724

Détail du produit anti-EPH Receptor A2 anticorps

Antigène: EPH Receptor A2 (EPHA2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor A2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Cell-ELISA (cELISA)

Specificité: Anti-human EphA2

Purification: Protein G

Immunogène: genetic immunisation with cDNA encoding human EphA2

Clone: Kalpha-5H5

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Commentaires:

Synonyms: Eph receptor tyrosine kinase A2

Restrictions: For Research Use only

Stockage

Concentration: 2 mg/mL

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur EPH Receptor A2

Antigène: EPH Receptor A2 (EPHA2)

Autre désignation: EPHA2 (EPHA2 Produits)

Synonymes: anticorps ARCC2, anticorps CTPA, anticorps CTPP1, anticorps CTRCT6, anticorps ECK, anticorps epha2, anticorps MGC89505, anticorps AW545284, anticorps Eck, anticorps Myk2, anticorps Sek-2, anticorps Sek2, anticorps id:ibd5152, anticorps rtk6, anticorps G42, anticorps XE10, anticorps epha2-A, anticorps EPH receptor A2, anticorps Eph receptor A2, anticorps epoxide hydrolase, anticorps eph receptor A2 a, anticorps EPH receptor A2 L homeolog, anticorps EPHA2, anticorps Epha2, anticorps epha2, anticorps ephA2, anticorps epha2a, anticorps epha2.L

Sujet: EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.

UniProt: P29317

Pathways: Signalisation RTK