CD74 anticorps
-
- Antigène Voir toutes CD74 Anticorps
- CD74 (HLA-DR-gamma (CD74))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp CD74 est non-conjugé
-
Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificité
- This antibody recognizes Human CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Bu45 antibody recognizes 33, 35 and 41 kDa isoforms of CD74.
- Attributs du produit
- Synonyms: p33, DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DRantigens-associated invariant chain, Ia antigen-associated invariant chain
- Purification
- Affinity chromatography on Protein G
- Immunogène
- B lymphoblastoid cell line HFB1. Spleen cells from immunised mice were fused with cells ofthe Ag8. 653 myeloma cell line. Genename: CD74
- Clone
- Bu45
- Isotype
- IgG1
- Top Product
- Discover our top product CD74 Anticorps primaire
-
-
- Indications d'application
-
Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/25 - 1/50,use 10 μL of the suggested working dilution to label 1x106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0mg/mL
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
-
Store at +4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch. - Date de péremption
- 12 months
-
- Antigène
- CD74 (HLA-DR-gamma (CD74))
- Autre désignation
- CD74 (CD74 Produits)
- Synonymes
- anticorps DHLAG, anticorps HLADG, anticorps II, anticorps Ia-GAMMA, anticorps CLIP, anticorps Ii, anticorps INVG34, anticorps Iclp-1, anticorps iclp1, anticorps wu:fb11f09, anticorps wu:fb12a01, anticorps wu:fb13d06, anticorps wu:fk94e07, anticorps Iclp-2, anticorps cd74, anticorps iclp2, anticorps zgc:123161, anticorps CD74 molecule, anticorps CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), anticorps CD74 molecule, major histocompatibility complex, class II invariant chain a, anticorps CD74 molecule, major histocompatibility complex, class II invariant chain b, anticorps CD74, anticorps Cd74, anticorps cd74a, anticorps cd74b
- Sujet
- The CD74 Molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 Molecule, which is distal from the C-terminus.Synonyms: DHLAG, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, p33
- ID gène
- 972
- UniProt
- P04233
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
-