GM-CSF anticorps

N° du produit ABIN180855

Détail du produit anti-GM-CSF anticorps

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GM-CSF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificité: When immobilised on a microplate, this antibody will capture recombinant and natural GM-CSF.

Attributs du produit: Synonyms: CSF2, GMCSF, Sargramostim, Molgramostin, Granulocyte-macrophage colony-stimulatingfactor, Colony stimulating factor 2

Purification: Protein A chromatography, 0.2µm sterile filtered

Immunogène: R-DNA. Genename: GM-CSF

Clone: 30-04-14

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on frozen sections: used at 25g/mLELISA: 1/1K - 1/2K. Western Blot: used at 1-2g/mLFunctional Assays: The neutralisation dose (ND50) of this batch was determined to beapproximately 0.3-0.5 μg/mL in the presence of 0.5 ng/mL of recombinant human GM-CSF. ND50 may vary depending on conditions. ND50 is defined as the concentration of Abrequired to yield half maximal inhibition of cytokine activity on a responsive cell line, whenthat cytokine is present at a concentration just high enough to elicit a maximum response.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 with 1 % Trehalose

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GM-CSF

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: GM-CSF (CSF2 Produits)

Synonymes: anticorps GMCSF, anticorps GM-CSF, anticorps CSF2, anticorps Csfgm, anticorps Gm-CSf, anticorps MGI-IGM, anticorps Gm-csf, anticorps Gmcsf, anticorps CSF, anticorps colony stimulating factor 2, anticorps colony stimulating factor 2 (granulocyte-macrophage), anticorps CSF2, anticorps Csf2

Sujet: The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim

ID gène: 1437

UniProt: P04141

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin