Complement Factor B anticorps (Fragment Bb)

N° du produit ABIN181113

Détail du produit anti-Complement Factor B anticorps

Antigène: Complement Factor B (CFB)

Épitope: Fragment Bb

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement Factor B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody recognises the Bb fragment of 90 kDa complement factor B, present in blood serum.

Attributs du produit: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Purification: Affinity chromatography on Protein A

Immunogène: Human factor B

Clone: 10-09-14

Isotype: IgG1

Information d'application

Indications d'application: ELISA: This antibody binds to both the Bb fragment and complement factor B so is notsuitable for all ELISA applications. Western Blot. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptocial glomerlulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Borate buffered saline containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Complement Factor B

Antigène: Complement Factor B (CFB)

Autre désignation: Complement Factor B (CFB Produits)

Synonymes: anticorps AHUS4, anticorps BF, anticorps BFD, anticorps CFAB, anticorps FB, anticorps FBI12, anticorps GBG, anticorps H2-Bf, anticorps PBF2, anticorps bf, anticorps Bf-1, anticorps Brre-Bf, anticorps zgc:114032, anticorps Bf, anticorps Sp152, anticorps bfb-A, anticorps Bf B, anticorps LOC397725, anticorps bf/c2, anticorps CFB, anticorps AI195813, anticorps AI255840, anticorps B, anticorps C2, anticorps Fb, anticorps Da1-24, anticorps complement factor B, anticorps complement factor B S homeolog, anticorps complement factor B L homeolog, anticorps CFB, anticorps cfb, anticorps bf, anticorps cfb.S, anticorps cfb.L, anticorps bf/c2, anticorps LOC100555981, anticorps Cfb

Sujet: C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

ID gène: 629

UniProt: P00751

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process