Complement Factor B anticorps (AA 469-494)
Aperçu rapide pour Complement Factor B anticorps (AA 469-494) (ABIN652979)
Antigène
Voir toutes Complement Factor B (CFB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 469-494
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This CFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-494 amino acids from the Central region of human CFB.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- Complement Factor B (CFB)
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Autre désignation
- CFB
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Sujet
- CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
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Poids moléculaire
- 85533
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ID gène
- 629
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NCBI Accession
- NP_001701
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UniProt
- P00751
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Pathways
- Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process
Antigène
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