ITGA6 anticorps (PE)
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- Antigène Voir toutes ITGA6 Anticorps
- ITGA6 (Integrin, alpha 6 (ITGA6))
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Reactivité
- Humain, Souris, Chien, Porc, Singe
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ITGA6 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody recognises CD49F (VLA-6 alpha chain). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. We recommend the use of SM038Afor this purpose.
- Purification
- Affinity chromatography on Protein G
- Immunogène
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
- Clone
- NKI-GoH3
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGA6 Anticorps primaire
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- Indications d'application
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Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1.0 mL distilled water.
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Autre désignation
- CD49f / ITGA6 (ITGA6 Produits)
- Synonymes
- anticorps CD49f, anticorps ITGA6B, anticorps VLA-6, anticorps 5033401O05Rik, anticorps AI115430, anticorps Cd49f, anticorps ITGA6, anticorps inta6, anticorps im:6897425, anticorps itga6, anticorps si:dkey-32o22.1, anticorps wu:fb80g02, anticorps LOC100221694, anticorps si:dkey-18j14.1, anticorps wu:fl20e08, anticorps zgc:113088, anticorps integrin subunit alpha 6, anticorps integrin alpha 6, anticorps integrin subunit alpha 6 L homeolog, anticorps integrin, alpha 6a, anticorps integrin, alpha 6b, anticorps ITGA6, anticorps Itga6, anticorps itga6.L, anticorps itga6a, anticorps itga6b
- Sujet
- CD49F (VLA-6 alpha chain)is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
- ID gène
- 3655
- NCBI Accession
- NP_000201
- UniProt
- P23229
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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