Interferon gamma anticorps

N° du produit ABIN181786

Cet anticorps Souris Monoclonal détecte spécifiquement Interferon gamma dans EIA et IHC (fro). Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour Interferon gamma anticorps (ABIN181786)

Antigène: Interferon gamma (IFNG)

Reactivité: Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DB1

Détail du produit anti-Interferon gamma anticorps

Specificité: This antibody reacts with IFN-gamma. Clone DB-1 exhibits high affinity binding to the natural and recombinant forms and effectively neutralises the anti viral activity of IFN-gamma. It also blocks the induction of Ia antigen expression on murine keratinocytes. There is no cross-reaction with rodent IFN-alpha or IFN-beta or with human interferons. Clone DB-1 has also been reported for use in neutralising studies. MCA1301XZ is recommended for this purpose.

Purification: Purified

Immunogène: Recombinant rat IFN gamma.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 10 μg/mL - 100 μg/mL. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 125 mM trehalose and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFNG / Interferon gamma

Sujet: Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.Synonyms: IFN-gamma, gamma IFN

ID gène: 15978

NCBI Accession: NP_032363

UniProt: P01580

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy