CD19 anticorps (APC)

N° du produit ABIN181826

Détail du produit anti-CD19 anticorps (APC)

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD19 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Specificité: This antibody recognizes the CD19 cell surface antigen. It labels all B lymphocytes in peripheral blood and spleen but is negative on granulocytes, monocytes, platelets, T lymphocytes and erythrocytes. This antibody is useful for enumerating normal B lymphocytes and typing B cell malignancies by Flow cytometry and Immunofluorescence. The antibody reacts with most B cell malignancies including chronic leukaemia and most lymphomas, but not multiple myeloma.

Clone: LT19

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water.

Buffer: PBS, pH 7.4, containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C for one month. Prior to reconstitution store at -20 °C for one year or following reconstitution at -20 °C for 6 month.

Date de péremption: 12 months

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19 (CD19 Produits)

Synonymes: anticorps B4, anticorps CVID3, anticorps AW495831, anticorps CD19, anticorps CD19 molecule, anticorps CD19 antigen, anticorps CD19, anticorps Cd19

Sujet: CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 Molecule is expressed on 100 % of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10 % of normal human peripheral blood cells and approximately 60 % of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12 % of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12

ID gène: 930

NCBI Accession: NP_001171569

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway