CD14 anticorps

N° du produit ABIN1819121

L’anticorps Souris Monoclonal anti-CD14 a été validé pour FACS et IF. Il convient pour détecter CD14 dans des échantillons de Humain, Boeuf (Vache), Mouton et Water Buffalo.

Aperçu rapide pour CD14 anticorps (ABIN1819121)

Antigène: CD14

Reactivité: Humain, Boeuf (Vache), Mouton, Water Buffalo

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: CC-G33

Détail du produit anti-CD14 anticorps

Specificité: Recognizing bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14, see for details. CC-G33 has also been shown to be reactive with CD14 from the Water buffalo.

Purification: Protein G purified

Immunogène: Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.

Type of Immunogen: Purified protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

ID gène: 929

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades