P-Selectin anticorps (PE)

N° du produit ABIN181983

Détail du produit anti-P-Selectin anticorps (PE)

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Chévre, Cat, Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-Selectin.

Attributs du produit: Absorption / Emission: 488nm / 575nm

Purification: Affinity Chromatography on Protein G.

Immunogène: P-selectin transfected 300.19 cells.

Clone: Psel-KO-2-7

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of Neat-1/5 diluted antibody to label 106 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.0 mL distilled water

Concentration: approx. 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: CD62P / P-Selectin (SELP Produits)

Synonymes: anticorps PSELECT, anticorps CD62, anticorps CD62P, anticorps GMP140, anticorps GRMP, anticorps LECAM3, anticorps PADGEM, anticorps PSEL, anticorps GMP-140, anticorps Grmp, anticorps selectin P, anticorps selectin, platelet, anticorps Selp, anticorps SELP

Sujet: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond clusterSynonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

ID gène: 6403

NCBI Accession: NP_002996

UniProt: P16109