CD47 anticorps
Aperçu rapide pour CD47 anticorps (ABIN6796388)
Antigène
Voir toutes CD47 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.
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Purification
- Protein G purified
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Immunogène
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Human erythrocytes.
Type of Immunogen: Cells -
Isotype
- IgG2b
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Indications d'application
- Approved: Flo (1:25 - 1:100), IHC, IHC-Fr, IP
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Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- CD47
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Autre désignation
- CD47
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Sujet
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Name/Gene ID: CD47
Synonyms: CD47, CD47 antigen, CD47 Molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP -
ID gène
- 961
Antigène
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