CD14 anticorps (FITC)
Aperçu rapide pour CD14 anticorps (FITC) (ABIN1819883)
Antigène
Voir toutes CD14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Clone CC-G33 cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14.
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Purification
- Protein G purified
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Immunogène
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Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Indications d'application
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Approved: Flo, IF
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Bovine
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Protect from light.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- CD14
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Autre désignation
- CD14
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Sujet
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Name/Gene ID: CD14
Synonyms: CD14, CD14 Molecule, CD14 antigen -
ID gène
- 929
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
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