ITGAL anticorps

N° du produit ABIN1837566

Cet anticorps anti-ITGAL est un anticorps Souris Monoclonal détectant ITGAL dans FACS, IHC et IHC (fro). Adapté pour Souris.

Aperçu rapide pour ITGAL anticorps (ABIN1837566)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 87-6F9

Détail du produit anti-ITGAL anticorps

Specificité: CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin 9-2). A defect in 9-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.

Purification: Purified

Immunogène:

Type of Immunogen: Native protein

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C.

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: LFA-1 / CD11A

Sujet: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

ID gène: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex