APOA5 anticorps (AA 20-363)

N° du produit ABIN1842850

Cet anticorps Souris Monoclonal détecte spécifiquement APOA5 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour APOA5 anticorps (AA 20-363) (ABIN1842850)

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOA5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-APOA5 anticorps

Épitope: AA 20-363

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur APOA5

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: Apoa5

Sujet: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

Poids moléculaire: 41 kDa

ID gène: 116519

UniProt: Q6Q788

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism