Integrin Alpha2b anticorps (AA 45-149)
Aperçu rapide pour Integrin Alpha2b anticorps (AA 45-149) (ABIN1844101)
Antigène
Voir toutes Integrin Alpha2b (CD41) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 45-149
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. coli.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- Integrin Alpha2b (CD41)
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Autre désignation
- ITGA2B
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Sujet
- ITGA2B encodes integrin alpha chain 2b.Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation.Mutations that interfere with this role result in thrombasthenia.In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
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Poids moléculaire
- 113.4 kDa
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ID gène
- 3674
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UniProt
- P08514
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Pathways
- Integrin Complex
Antigène
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