ALDH2 anticorps (AA 317-517)

N° du produit ABIN1846467

Cet anticorps anti-ALDH2 est un anticorps Souris Monoclonal détectant ALDH2 dans WB, IHC, ELISA, FACS et IF/ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ALDH2 anticorps (AA 317-517) (ABIN1846467)

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ALDH2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Détail du produit anti-ALDH2 anticorps

Épitope: AA 317-517

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur ALDH2

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Autre désignation: ALDH2

Sujet: This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations.Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 56.3 kDa

ID gène: 217